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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2020 | 23 | MLB | NL | PHI | 0 | 0 | --- | 0 | 12 | 0 | 2 | 0 | 0 | 10.2 | 13 | 10 | 9 | 1 | 2 | 0 | 10 | 2 | 2 | 7.59 | 1.41 | | 2021 | 24 | MLB | NL | PHI | 0 | 0 | --- | 0 | 11 | 0 | 1 | 0 | 0 | 9.0 | 12 | 8 | 7 | 4 | 4 | 1 | 8 | 1 | 3 | 7.00 | 1.78 | | 2022 | 25 | MLB | NL | PHI | 0 | 0 | --- | 0 | 2 | 0 | 1 | 0 | 0 | 2.0 | 4 | 3 | 3 | 1 | 1 | 0 | 1 | 0 | 1 | 13.50 | 2.50 | | 2022 | 25 | MLB | NL | STL | 0 | 0 | --- | 0 | 15 | 0 | 4 | 0 | 0 | 14.1 | 9 | 6 | 6 | 2 | 9 | 0 | 16 | 0 | 4 | 3.77 | 1.26 | | 2022 | 25 | MLB | NL | TOT | 0 | 0 | --- | 0 | 17 | 0 | 5 | 0 | 0 | 16.1 | 13 | 9 | 9 | 3 | 10 | 0 | 17 | 0 | 5 | 4.96 | 1.41 | | 2023 | 26 | MLB | NL | STL | 4 | 2 | .667 | 3 | 27 | 0 | 13 | 0 | 0 | 36.2 | 29 | 17 | 15 | 1 | 10 | 0 | 42 | 1 | 5 | 3.68 | 1.06 | | 2024 | 27 | MLB | NL | STL | 7 | 3 | .700 | 1 | 65 | 0 | 7 | 0 | 0 | 59.0 | 52 | 23 | 22 | 8 | 16 | 0 | 51 | 5 | 5 | 3.36 | 1.15 | | 2025 | 28 | MLB | NL | STL | 4 | 6 | .400 | 8 | 65 | 0 | 16 | 0 | 0 | 61.0 | 47 | 21 | 14 | 2 | 29 | 5 | 55 | 2 | 6 | 2.07 | 1.25 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Career | PHI | 0 | 0 | --- | 0 | 25 | 0 | 4 | 0 | 0 | 21.2 | 29 | 21 | 19 | 6 | 7 | 1 | 19 | 3 | 6 | 7.89 | 1.66 | | Career | STL | 15 | 11 | .577 | 12 | 172 | 0 | 40 | 0 | 0 | 171.0 | 137 | 67 | 57 | 13 | 64 | 5 | 164 | 8 | 20 | 3.00 | 1.18 | | Career | Majors | 15 | 11 | .577 | 12 | 197 | 0 | 44 | 0 | 0 | 192.2 | 166 | 88 | 76 | 19 | 71 | 6 | 183 | 11 | 26 | 3.55 | 1.23 |
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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2020 | 23 | MLB | NL | PHI | | | | | | | | | | 5.2 | 5 | 6 | 6 | 1 | 2 | 0 | 6 | 2 | 0 | 9.53 | 1.24 | | 2020 | 23 | MLB | NL | PHI | | | | | | | | | | 5.0 | 8 | 4 | 3 | 0 | 0 | 0 | 4 | 0 | 2 | 5.40 | 1.60 | | 2021 | 24 | MLB | NL | PHI | | | | | | | | | | 4.1 | 5 | 4 | 3 | 1 | 3 | 0 | 5 | 1 | 0 | 6.23 | 1.85 | | 2021 | 24 | MLB | NL | PHI | | | | | | | | | | 4.2 | 7 | 4 | 4 | 3 | 1 | 1 | 3 | 0 | 3 | 7.71 | 1.71 | | 2022 | 25 | MLB | | TOT | | | | | | | | | | 5.1 | 2 | 3 | 3 | 1 | 5 | 0 | 10 | 0 | 0 | 5.06 | 1.31 | | 2022 | 25 | MLB | | TOT | | | | | | | | | | 11.0 | 11 | 6 | 6 | 2 | 5 | 0 | 7 | 0 | 5 | 4.91 | 1.45 | | 2023 | 26 | MLB | NL | STL | | | | | | | | | | 12.1 | 4 | 2 | 2 | 0 | 3 | 0 | 12 | 0 | 2 | 1.46 | 0.57 | | 2023 | 26 | MLB | NL | STL | | | | | | | | | | 24.1 | 25 | 15 | 13 | 1 | 7 | 0 | 30 | 1 | 3 | 4.81 | 1.32 | | 2024 | 27 | MLB | NL | STL | | | | | | | | | | 20.2 | 13 | 5 | 5 | 1 | 5 | 0 | 25 | 1 | 1 | 2.18 | 0.87 | | 2024 | 27 | MLB | NL | STL | | | | | | | | | | 38.1 | 39 | 18 | 17 | 7 | 11 | 0 | 26 | 4 | 4 | 3.99 | 1.30 | | 2025 | 28 | MLB | NL | STL | | | | | | | | | | 25.0 | 19 | 5 | 3 | 0 | 9 | 0 | 27 | 1 | 1 | 1.08 | 1.12 | | 2025 | 28 | MLB | NL | STL | | | | | | | | | | 36.0 | 28 | 16 | 11 | 2 | 20 | 5 | 28 | 1 | 5 | 2.75 | 1.33 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Career | vs LH | | | | | | | | | | 73.1 | 48 | 25 | 22 | 4 | 27 | 0 | 85 | 5 | 4 | 2.70 | 1.02 | | Career | vs RH | | | | | | | | | | 119.1 | 118 | 63 | 54 | 15 | 44 | 6 | 98 | 6 | 22 | 4.07 | 1.36 |
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