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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2014 | 21 | R | GCL | TOR | 0 | 0 | --- | 0 | 2 | 0 | 2 | 0 | 0 | 3.0 | 2 | 0 | 0 | 0 | 4 | 0 | 1 | 0 | 0 | 0.00 | 2.00 | | 2014 | 21 | R | APP | TOR | 1 | 1 | .500 | 0 | 11 | 0 | 4 | 0 | 0 | 25.0 | 19 | 7 | 6 | 0 | 9 | 0 | 33 | 2 | 0 | 2.16 | 1.12 | | 2016 | 23 | A | MWL | TOR | 3 | 2 | .600 | 0 | 15 | 14 | 0 | 1 | 0 | 72.2 | 49 | 24 | 17 | 3 | 27 | 0 | 72 | 5 | 0 | 2.11 | 1.05 | | 2017 | 24 | A+ | FSL | | 7 | 5 | .583 | 0 | 28 | 26 | 0 | 0 | 0 | 138.0 | 141 | 65 | 52 | 2 | 54 | 0 | 138 | 14 | 0 | 3.39 | 1.41 | | 2018 | 25 | AA | EAS | | 11 | 8 | .579 | 0 | 25 | 25 | 0 | 0 | 0 | 137.0 | 122 | 80 | 63 | 15 | 41 | 0 | 125 | 7 | 0 | 4.14 | 1.19 | | 2018 | 25 | AAA | INT | | 1 | 0 | 1.000 | 0 | 1 | 1 | 0 | 0 | 0 | 5.0 | 4 | 2 | 2 | 0 | 4 | 0 | 3 | 0 | 0 | 3.60 | 1.60 | | 2019 | 26 | R | GCL | | 0 | 0 | --- | 0 | 1 | 0 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | | 2019 | 26 | AAA | INT | | 2 | 2 | .500 | 5 | 24 | 3 | 13 | 0 | 0 | 37.2 | 37 | 26 | 24 | 8 | 14 | 0 | 53 | 4 | 0 | 5.73 | 1.35 | | 2019 | 26 | MLB | AL | TOR | 0 | 2 | .000 | 0 | 17 | 0 | 2 | 0 | 0 | 15.1 | 17 | 14 | 13 | 4 | 9 | 0 | 21 | 4 | 1 | 7.63 | 1.70 | | 2020 | 27 | MLB | AL | TOR | 2 | 1 | .667 | 2 | 15 | 0 | 3 | 0 | 0 | 14.2 | 8 | 3 | 2 | 2 | 5 | 0 | 21 | 0 | 0 | 1.23 | 0.89 | | 2021 | 28 | MLB | AL | TOR | 7 | 1 | .875 | 23 | 62 | 0 | 43 | 0 | 0 | 63.0 | 41 | 17 | 15 | 7 | 25 | 0 | 85 | 1 | 1 | 2.14 | 1.05 | | 2022 | 29 | MLB | AL | TOR | 5 | 4 | .556 | 36 | 63 | 0 | 52 | 0 | 0 | 64.0 | 44 | 18 | 15 | 4 | 21 | 4 | 73 | 4 | 5 | 2.11 | 1.02 | | 2023 | 30 | MLB | AL | TOR | 5 | 7 | .417 | 36 | 59 | 0 | 49 | 0 | 0 | 59.0 | 48 | 20 | 19 | 6 | 24 | 5 | 72 | 2 | 3 | 2.90 | 1.22 | | 2024 | 31 | MLB | AL | TOR | 1 | 2 | .333 | 8 | 15 | 0 | 14 | 0 | 0 | 13.2 | 16 | 10 | 10 | 4 | 4 | 1 | 13 | 1 | 0 | 6.59 | 1.46 | | 2025 | 32 | MLB | NL | PHI | 2 | 4 | .333 | 8 | 49 | 0 | 14 | 0 | 0 | 42.2 | 45 | 40 | 39 | 10 | 17 | 1 | 47 | 3 | 2 | 8.23 | 1.45 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Minors | Minors | 25 | 18 | .581 | 5 | 107 | 69 | 19 | 1 | 0 | 419.1 | 374 | 204 | 164 | 28 | 153 | 0 | 425 | 32 | 0 | 3.52 | 1.26 | | Career | TOR | 20 | 17 | .541 | 105 | 231 | 0 | 163 | 0 | 0 | 229.2 | 174 | 82 | 74 | 27 | 88 | 10 | 285 | 12 | 10 | 2.90 | 1.14 | | Career | PHI | 2 | 4 | .333 | 8 | 49 | 0 | 14 | 0 | 0 | 42.2 | 45 | 40 | 39 | 10 | 17 | 1 | 47 | 3 | 2 | 8.23 | 1.45 | | Career | Majors | 22 | 21 | .512 | 113 | 280 | 0 | 177 | 0 | 0 | 272.1 | 219 | 122 | 113 | 37 | 105 | 11 | 332 | 15 | 12 | 3.73 | 1.19 |
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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2019 | 26 | MLB | AL | TOR | | | | | | | | | | 7.1 | 5 | 3 | 2 | 1 | 5 | 0 | 10 | 1 | 1 | 2.45 | 1.36 | | 2019 | 26 | MLB | AL | TOR | | | | | | | | | | 8.0 | 12 | 11 | 11 | 3 | 4 | 0 | 11 | 3 | 0 | 12.38 | 2.00 | | 2020 | 27 | MLB | AL | TOR | | | | | | | | | | 7.1 | 2 | 2 | 1 | 1 | 1 | 0 | 14 | 0 | 0 | 1.23 | 0.41 | | 2020 | 27 | MLB | AL | TOR | | | | | | | | | | 7.1 | 6 | 1 | 1 | 1 | 4 | 0 | 7 | 0 | 0 | 1.23 | 1.36 | | 2021 | 28 | MLB | AL | TOR | | | | | | | | | | 27.1 | 13 | 5 | 4 | 2 | 7 | 0 | 43 | 1 | 0 | 1.32 | 0.73 | | 2021 | 28 | MLB | AL | TOR | | | | | | | | | | 35.2 | 28 | 12 | 11 | 5 | 18 | 0 | 42 | 0 | 1 | 2.78 | 1.29 | | 2022 | 29 | MLB | AL | TOR | | | | | | | | | | 29.0 | 22 | 8 | 6 | 2 | 10 | 2 | 38 | 0 | 1 | 1.86 | 1.10 | | 2022 | 29 | MLB | AL | TOR | | | | | | | | | | 35.0 | 22 | 10 | 9 | 2 | 11 | 2 | 35 | 4 | 4 | 2.31 | 0.94 | | 2023 | 30 | MLB | AL | TOR | | | | | | | | | | 25.1 | 22 | 12 | 12 | 5 | 12 | 2 | 34 | 0 | 0 | 4.26 | 1.34 | | 2023 | 30 | MLB | AL | TOR | | | | | | | | | | 33.2 | 26 | 8 | 7 | 1 | 12 | 3 | 38 | 2 | 3 | 1.87 | 1.13 | | 2024 | 31 | MLB | AL | TOR | | | | | | | | | | 7.2 | 7 | 4 | 4 | 2 | 2 | 1 | 9 | 0 | 0 | 4.70 | 1.17 | | 2024 | 31 | MLB | AL | TOR | | | | | | | | | | 6.0 | 9 | 6 | 6 | 2 | 2 | 0 | 4 | 1 | 0 | 9.00 | 1.83 | | 2025 | 32 | MLB | NL | PHI | | | | | | | | | | 19.1 | 19 | 18 | 17 | 5 | 6 | 1 | 27 | 1 | 0 | 7.91 | 1.29 | | 2025 | 32 | MLB | NL | PHI | | | | | | | | | | 23.1 | 26 | 22 | 22 | 5 | 11 | 0 | 20 | 2 | 2 | 8.49 | 1.59 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Career | vs LH | | | | | | | | | | 123.1 | 90 | 52 | 46 | 18 | 43 | 6 | 175 | 3 | 2 | 3.36 | 1.08 | | Career | vs RH | | | | | | | | | | 149.0 | 129 | 70 | 67 | 19 | 62 | 5 | 157 | 12 | 10 | 4.05 | 1.28 |
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