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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2010 | 17 | R | DSL | BAL | 3 | 4 | .429 | 0 | 12 | 12 | 0 | 1 | 1 | 65.2 | 49 | 26 | 17 | 0 | 28 | 0 | 62 | 0 | 0 | 2.33 | 1.17 | | 2011 | 18 | R | GCL | BAL | 1 | 1 | .500 | 1 | 11 | 10 | 1 | 0 | 0 | 44.2 | 28 | 17 | 9 | 0 | 17 | 0 | 46 | 2 | 0 | 1.81 | 1.01 | | 2011 | 18 | A- | NYP | BAL | 0 | 0 | --- | 0 | 1 | 1 | 0 | 0 | 0 | 4.0 | 6 | 3 | 3 | 1 | 1 | 0 | 4 | 0 | 0 | 6.75 | 1.75 | | 2012 | 19 | A | SAL | BAL | 5 | 7 | .417 | 0 | 22 | 22 | 0 | 1 | 0 | 107.0 | 103 | 56 | 44 | 4 | 30 | 0 | 73 | 5 | 0 | 3.70 | 1.24 | | 2013 | 20 | A+ | CAR | BAL | 6 | 4 | .600 | 0 | 14 | 14 | 0 | 0 | 0 | 85.0 | 78 | 36 | 27 | 4 | 25 | 0 | 66 | 2 | 0 | 2.86 | 1.21 | | 2013 | 20 | AA | EAS | BAL | 4 | 3 | .571 | 0 | 11 | 11 | 0 | 1 | 0 | 59.2 | 53 | 28 | 28 | 5 | 24 | 1 | 59 | 2 | 0 | 4.22 | 1.29 | | 2014 | 21 | AA | EAS | BOS | 3 | 1 | .750 | 0 | 6 | 6 | 0 | 0 | 0 | 37.1 | 30 | 4 | 4 | 1 | 8 | 0 | 39 | 2 | 0 | 0.96 | 1.02 | | 2014 | 21 | AA | EAS | BAL | 3 | 7 | .300 | 0 | 16 | 16 | 0 | 1 | 0 | 82.2 | 90 | 50 | 44 | 5 | 29 | 1 | 69 | 0 | 0 | 4.79 | 1.44 | | 2015 | 22 | AAA | INT | BOS | 4 | 3 | .571 | 0 | 8 | 8 | 0 | 1 | 0 | 48.1 | 46 | 22 | 16 | 2 | 7 | 0 | 44 | 0 | 0 | 2.98 | 1.10 | | 2015 | 22 | MLB | AL | BOS | 10 | 6 | .625 | 0 | 21 | 21 | 0 | 0 | 0 | 121.2 | 120 | 55 | 52 | 13 | 37 | 1 | 98 | 4 | 8 | 3.85 | 1.29 | | 2016 | 23 | AAA | INT | BOS | 0 | 4 | .000 | 0 | 7 | 7 | 0 | 0 | 0 | 38.0 | 33 | 15 | 13 | 6 | 7 | 0 | 24 | 1 | 0 | 3.08 | 1.05 | | 2016 | 23 | MLB | AL | BOS | 3 | 7 | .300 | 0 | 20 | 20 | 0 | 0 | 0 | 107.0 | 99 | 58 | 56 | 16 | 39 | 1 | 100 | 3 | 3 | 4.71 | 1.29 | | 2017 | 24 | AA | EAS | | 0 | 1 | .000 | 0 | 1 | 1 | 0 | 0 | 0 | 3.0 | 9 | 6 | 5 | 1 | 0 | 0 | 3 | 0 | 0 | 15.00 | 3.00 | | 2017 | 24 | AAA | INT | | 0 | 1 | .000 | 0 | 2 | 2 | 0 | 0 | 0 | 10.0 | 10 | 5 | 5 | 0 | 5 | 0 | 12 | 1 | 0 | 4.50 | 1.50 | | 2017 | 24 | MLB | AL | BOS | 6 | 7 | .462 | 0 | 25 | 24 | 1 | 0 | 0 | 137.1 | 126 | 66 | 64 | 19 | 50 | 1 | 150 | 5 | 6 | 4.19 | 1.28 | | 2018 | 25 | AA | EAS | | 0 | 0 | --- | 0 | 2 | 2 | 0 | 0 | 0 | 8.0 | 3 | 0 | 0 | 0 | 4 | 0 | 14 | 0 | 0 | 0.00 | 0.88 | | 2018 | 25 | MLB | AL | BOS | 13 | 5 | .722 | 0 | 27 | 23 | 0 | 0 | 0 | 129.2 | 119 | 56 | 55 | 16 | 45 | 1 | 146 | 4 | 5 | 3.82 | 1.26 | | 2019 | 26 | MLB | AL | BOS | 19 | 6 | .760 | 0 | 34 | 34 | 0 | 0 | 0 | 203.1 | 195 | 88 | 86 | 24 | 75 | 2 | 213 | 7 | 20 | 3.81 | 1.33 | | 2021 | 28 | MLB | AL | BOS | 13 | 8 | .619 | 0 | 32 | 31 | 0 | 0 | 0 | 157.2 | 172 | 87 | 83 | 19 | 47 | 0 | 185 | 2 | 14 | 4.74 | 1.39 | | 2022 | 29 | MLB | AL | DET | 5 | 5 | .500 | 0 | 17 | 17 | 0 | 0 | 0 | 91.0 | 87 | 49 | 41 | 12 | 34 | 0 | 72 | 2 | 10 | 4.05 | 1.33 | | 2023 | 30 | MLB | AL | DET | 13 | 9 | .591 | 0 | 26 | 26 | 0 | 0 | 0 | 152.2 | 128 | 59 | 56 | 15 | 48 | 0 | 143 | 3 | 11 | 3.30 | 1.15 | | 2024 | 31 | MLB | NL | ARI | 3 | 4 | .429 | 0 | 10 | 10 | 0 | 0 | 0 | 50.0 | 56 | 29 | 28 | 8 | 19 | 1 | 47 | 1 | 2 | 5.04 | 1.50 | | 2025 | 32 | MLB | NL | ARI | 9 | 9 | .500 | 0 | 29 | 29 | 0 | 0 | 0 | 154.1 | 178 | 94 | 86 | 25 | 60 | 2 | 143 | 1 | 8 | 5.02 | 1.54 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Minors | Minors | 29 | 36 | .446 | 1 | 113 | 112 | 1 | 5 | 1 | 593.1 | 538 | 268 | 215 | 29 | 185 | 2 | 515 | 15 | 0 | 3.26 | 1.22 | | Career | BOS | 64 | 39 | .621 | 0 | 159 | 153 | 1 | 0 | 0 | 856.2 | 831 | 410 | 396 | 107 | 293 | 6 | 892 | 25 | 56 | 4.16 | 1.31 | | Career | DET | 18 | 14 | .563 | 0 | 43 | 43 | 0 | 0 | 0 | 243.2 | 215 | 108 | 97 | 27 | 82 | 0 | 215 | 5 | 21 | 3.58 | 1.22 | | Career | ARI | 12 | 13 | .480 | 0 | 39 | 39 | 0 | 0 | 0 | 204.1 | 234 | 123 | 114 | 33 | 79 | 3 | 190 | 2 | 10 | 5.02 | 1.53 | | Career | Majors | 94 | 66 | .588 | 0 | 241 | 235 | 1 | 0 | 0 | 1304.2 | 1280 | 641 | 607 | 167 | 454 | 9 | 1297 | 32 | 87 | 4.19 | 1.33 |
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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2015 | 22 | MLB | AL | BOS | | | | | | | | | | 29.1 | 31 | 18 | 16 | 7 | 5 | 0 | 25 | 2 | 0 | 4.91 | 1.23 | | 2015 | 22 | MLB | AL | BOS | | | | | | | | | | 92.1 | 89 | 37 | 36 | 6 | 32 | 1 | 73 | 2 | 8 | 3.51 | 1.31 | | 2016 | 23 | MLB | AL | BOS | | | | | | | | | | 21.1 | 23 | 14 | 14 | 1 | 9 | 0 | 25 | 2 | 0 | 5.91 | 1.50 | | 2016 | 23 | MLB | AL | BOS | | | | | | | | | | 85.2 | 76 | 44 | 42 | 15 | 30 | 1 | 75 | 1 | 3 | 4.41 | 1.24 | | 2017 | 24 | MLB | AL | BOS | | | | | | | | | | 25.2 | 29 | 16 | 14 | 3 | 9 | 0 | 30 | 3 | 0 | 4.91 | 1.48 | | 2017 | 24 | MLB | AL | BOS | | | | | | | | | | 111.2 | 97 | 50 | 50 | 16 | 41 | 1 | 120 | 2 | 6 | 4.03 | 1.24 | | 2018 | 25 | MLB | AL | BOS | | | | | | | | | | 24.1 | 22 | 12 | 12 | 3 | 6 | 0 | 37 | 4 | 1 | 4.44 | 1.15 | | 2018 | 25 | MLB | AL | BOS | | | | | | | | | | 105.1 | 97 | 44 | 43 | 13 | 39 | 1 | 109 | 0 | 4 | 3.67 | 1.29 | | 2019 | 26 | MLB | AL | BOS | | | | | | | | | | 42.0 | 43 | 21 | 20 | 9 | 14 | 0 | 48 | 4 | 4 | 4.29 | 1.36 | | 2019 | 26 | MLB | AL | BOS | | | | | | | | | | 161.1 | 152 | 67 | 66 | 15 | 61 | 2 | 165 | 3 | 16 | 3.68 | 1.32 | | 2021 | 28 | MLB | AL | BOS | | | | | | | | | | 33.2 | 34 | 16 | 16 | 5 | 5 | 0 | 47 | 2 | 1 | 4.28 | 1.16 | | 2021 | 28 | MLB | AL | BOS | | | | | | | | | | 124.0 | 138 | 71 | 67 | 14 | 42 | 0 | 138 | 0 | 13 | 4.86 | 1.45 | | 2022 | 29 | MLB | AL | DET | | | | | | | | | | 16.2 | 20 | 10 | 7 | 3 | 11 | 0 | 15 | 1 | 4 | 3.78 | 1.86 | | 2022 | 29 | MLB | AL | DET | | | | | | | | | | 74.1 | 67 | 39 | 34 | 9 | 23 | 0 | 57 | 1 | 6 | 4.12 | 1.21 | | 2023 | 30 | MLB | AL | DET | | | | | | | | | | 34.2 | 23 | 12 | 12 | 2 | 12 | 0 | 36 | 0 | 0 | 3.12 | 1.01 | | 2023 | 30 | MLB | AL | DET | | | | | | | | | | 118.0 | 105 | 47 | 44 | 13 | 36 | 0 | 107 | 3 | 11 | 3.36 | 1.19 | | 2024 | 31 | MLB | NL | ARI | | | | | | | | | | 9.2 | 8 | 6 | 6 | 2 | 6 | 0 | 8 | 0 | 0 | 5.59 | 1.45 | | 2024 | 31 | MLB | NL | ARI | | | | | | | | | | 40.1 | 48 | 23 | 22 | 6 | 13 | 1 | 39 | 1 | 2 | 4.91 | 1.51 | | 2025 | 32 | MLB | NL | ARI | | | | | | | | | | 33.2 | 43 | 18 | 18 | 4 | 7 | 0 | 29 | 0 | 0 | 4.81 | 1.49 | | 2025 | 32 | MLB | NL | ARI | | | | | | | | | | 120.2 | 135 | 76 | 68 | 21 | 53 | 2 | 114 | 1 | 8 | 5.07 | 1.56 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Career | vs LH | | | | | | | | | | 271.0 | 276 | 143 | 135 | 39 | 84 | 0 | 300 | 18 | 10 | 4.48 | 1.33 | | Career | vs RH | | | | | | | | | | 1033.2 | 1004 | 498 | 472 | 128 | 370 | 9 | 997 | 14 | 77 | 4.11 | 1.33 |
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| Year | Age | Lvl | Lg | Org | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| 2015 | 22 | MLB | AL | BOS | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2016 | 23 | MLB | AL | BOS | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2017 | 24 | MLB | AL | BOS | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2018 | 25 | MLB | AL | BOS | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2019 | 26 | MLB | AL | BOS | 3 | 7 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 2 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2021 | 28 | MLB | AL | BOS | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | .000 | .000 | .000 | .000 | | Totals | | | | | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| Career | BOS | 12 | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13 | 0 | 0 | 3 | 0 | 0 | 1 | .000 | .000 | .000 | .000 | | Career | Majors | 12 | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13 | 0 | 0 | 3 | 0 | 0 | 1 | .000 | .000 | .000 | .000 |
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| Year | Age | Lvl | Lg | Org | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| 2015 | 22 | MLB | AL | BOS | | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2015 | 22 | MLB | AL | BOS | | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2016 | 23 | MLB | AL | BOS | | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | --- | --- | --- | --- | | 2016 | 23 | MLB | AL | BOS | | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2017 | 24 | MLB | AL | BOS | | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2017 | 24 | MLB | AL | BOS | | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2018 | 25 | MLB | AL | BOS | | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2018 | 25 | MLB | AL | BOS | | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2019 | 26 | MLB | AL | BOS | | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2019 | 26 | MLB | AL | BOS | | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 2 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | 2021 | 28 | MLB | AL | BOS | | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | .000 | .000 | .000 | .000 | | 2021 | 28 | MLB | AL | BOS | | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | Totals | | | | | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| Career | vs LH | | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 0 | 1 | .000 | .000 | .000 | .000 | | Career | vs RH | | 16 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | 2 | 0 | 0 | 0 | .000 | .000 | .000 | .000 |
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