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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2011 | 18 | R | DSL | COL | 3 | 2 | .600 | 0 | 8 | 6 | 1 | 1 | 0 | 34.0 | 33 | 14 | 13 | 2 | 14 | 0 | 27 | 0 | 0 | 3.44 | 1.38 | | 2012 | 19 | R | DSL | COL | 3 | 3 | .500 | 0 | 12 | 9 | 1 | 1 | 0 | 54.1 | 53 | 31 | 25 | 3 | 13 | 0 | 38 | 3 | 0 | 4.14 | 1.21 | | 2013 | 20 | R | PIO | COL | 5 | 1 | .833 | 0 | 22 | 0 | 4 | 0 | 0 | 35.2 | 31 | 18 | 15 | 3 | 14 | 0 | 31 | 1 | 0 | 3.79 | 1.26 | | 2013 | 20 | A- | NWL | COL | 1 | 0 | 1.000 | 0 | 2 | 0 | 0 | 0 | 0 | 3.2 | 3 | 1 | 1 | 1 | 1 | 0 | 5 | 0 | 0 | 2.45 | 1.09 | | 2014 | 21 | A | SAL | COL | 1 | 3 | .250 | 0 | 33 | 0 | 5 | 0 | 0 | 53.1 | 62 | 34 | 28 | 4 | 11 | 0 | 50 | 1 | 0 | 4.72 | 1.37 | | 2015 | 22 | A+ | CAL | COL | 5 | 0 | 1.000 | 5 | 14 | 0 | 10 | 0 | 0 | 19.1 | 12 | 3 | 3 | 0 | 5 | 0 | 25 | 0 | 0 | 1.40 | 0.88 | | 2015 | 22 | AA | EAS | COL | 0 | 3 | .000 | 13 | 34 | 0 | 26 | 0 | 0 | 36.0 | 39 | 19 | 18 | 2 | 9 | 0 | 43 | 1 | 0 | 4.50 | 1.33 | | 2016 | 23 | AAA | PCL | COL | 1 | 0 | 1.000 | 0 | 5 | 0 | 2 | 0 | 0 | 5.2 | 6 | 2 | 2 | 0 | 3 | 0 | 4 | 0 | 0 | 3.18 | 1.59 | | 2016 | 23 | MLB | NL | COL | 3 | 7 | .300 | 11 | 63 | 0 | 26 | 0 | 0 | 55.0 | 50 | 32 | 32 | 6 | 28 | 4 | 59 | 5 | 1 | 5.24 | 1.42 | | 2017 | 24 | AAA | PCL | | 1 | 4 | .200 | 4 | 33 | 0 | 19 | 0 | 0 | 33.2 | 23 | 6 | 5 | 2 | 10 | 0 | 34 | 1 | 0 | 1.34 | 0.98 | | 2017 | 24 | MLB | NL | COL | 5 | 0 | 1.000 | 0 | 35 | 0 | 9 | 0 | 0 | 32.1 | 39 | 21 | 20 | 3 | 14 | 2 | 31 | 1 | 3 | 5.57 | 1.64 | | 2018 | 25 | AAA | PCL | | 0 | 1 | .000 | 1 | 28 | 0 | 8 | 0 | 0 | 28.1 | 37 | 21 | 20 | 6 | 11 | 0 | 35 | 1 | 0 | 6.35 | 1.69 | | 2019 | 26 | MLB | NL | COL | 2 | 2 | .500 | 0 | 71 | 0 | 13 | 0 | 0 | 72.0 | 70 | 34 | 30 | 12 | 23 | 1 | 81 | 1 | 4 | 3.75 | 1.29 | | 2020 | 27 | MLB | NL | COL | 1 | 3 | .250 | 1 | 26 | 0 | 6 | 0 | 0 | 24.0 | 33 | 21 | 20 | 6 | 9 | 0 | 27 | 3 | 1 | 7.50 | 1.75 | | 2021 | 28 | MLB | NL | COL | 3 | 5 | .375 | 11 | 64 | 0 | 22 | 0 | 0 | 61.2 | 71 | 32 | 30 | 8 | 21 | 0 | 60 | 2 | 7 | 4.38 | 1.49 | | 2022 | 29 | MLB | NL | COL | 4 | 4 | .500 | 2 | 62 | 0 | 20 | 0 | 0 | 57.0 | 44 | 27 | 22 | 7 | 23 | 1 | 54 | 1 | 2 | 3.47 | 1.18 | | 2023 | 30 | MLB | AL | LAA | 5 | 5 | .500 | 31 | 63 | 0 | 49 | 0 | 0 | 62.1 | 62 | 34 | 27 | 7 | 31 | 5 | 78 | 5 | 3 | 3.90 | 1.49 | | 2024 | 31 | MLB | AL | LAA | 1 | 3 | .250 | 20 | 34 | 0 | 29 | 0 | 0 | 34.0 | 20 | 10 | 9 | 3 | 5 | 2 | 32 | 0 | 1 | 2.38 | 0.74 | | 2024 | 31 | MLB | NL | PHI | 3 | 2 | .600 | 6 | 20 | 0 | 18 | 0 | 0 | 21.0 | 18 | 8 | 6 | 2 | 7 | 2 | 18 | 1 | 1 | 2.57 | 1.19 | | 2024 | 31 | MLB | | TOT | 4 | 5 | .444 | 26 | 54 | 0 | 47 | 0 | 0 | 55.0 | 38 | 18 | 15 | 5 | 12 | 4 | 50 | 1 | 2 | 2.45 | 0.91 | | 2025 | 32 | MLB | AL | KC | 4 | 5 | .444 | 42 | 67 | 0 | 57 | 0 | 0 | 66.0 | 48 | 22 | 18 | 5 | 22 | 6 | 54 | 4 | 1 | 2.45 | 1.06 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Minors | Minors | 20 | 17 | .541 | 23 | 191 | 15 | 76 | 2 | 0 | 304.0 | 299 | 149 | 130 | 23 | 91 | 0 | 292 | 8 | 0 | 3.85 | 1.28 | | Career | COL | 18 | 21 | .462 | 25 | 321 | 0 | 96 | 0 | 0 | 302.0 | 307 | 167 | 154 | 42 | 118 | 8 | 312 | 13 | 18 | 4.59 | 1.41 | | Career | LAA | 6 | 8 | .429 | 51 | 97 | 0 | 78 | 0 | 0 | 96.1 | 82 | 44 | 36 | 10 | 36 | 7 | 110 | 5 | 4 | 3.36 | 1.22 | | Career | PHI | 3 | 2 | .600 | 6 | 20 | 0 | 18 | 0 | 0 | 21.0 | 18 | 8 | 6 | 2 | 7 | 2 | 18 | 1 | 1 | 2.57 | 1.19 | | Career | KC | 4 | 5 | .444 | 42 | 67 | 0 | 57 | 0 | 0 | 66.0 | 48 | 22 | 18 | 5 | 22 | 6 | 54 | 4 | 1 | 2.45 | 1.06 | | Career | Majors | 31 | 36 | .463 | 124 | 505 | 0 | 249 | 0 | 0 | 485.1 | 455 | 241 | 214 | 59 | 183 | 23 | 494 | 23 | 24 | 3.97 | 1.31 |
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| Year | Age | Lvl | Lg | Org | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| 2016 | 23 | MLB | NL | COL | | | | | | | | | | 23.0 | 15 | 11 | 11 | 0 | 14 | 3 | 21 | 2 | 1 | 4.30 | 1.26 | | 2016 | 23 | MLB | NL | COL | | | | | | | | | | 32.0 | 35 | 21 | 21 | 6 | 14 | 1 | 38 | 3 | 0 | 5.91 | 1.53 | | 2017 | 24 | MLB | NL | COL | | | | | | | | | | 12.2 | 19 | 9 | 8 | 0 | 6 | 2 | 9 | 0 | 2 | 5.68 | 1.97 | | 2017 | 24 | MLB | NL | COL | | | | | | | | | | 19.2 | 20 | 12 | 12 | 3 | 8 | 0 | 22 | 1 | 1 | 5.49 | 1.42 | | 2019 | 26 | MLB | NL | COL | | | | | | | | | | 29.2 | 35 | 16 | 14 | 5 | 14 | 1 | 24 | 0 | 1 | 4.25 | 1.65 | | 2019 | 26 | MLB | NL | COL | | | | | | | | | | 42.1 | 35 | 18 | 16 | 7 | 9 | 0 | 57 | 1 | 3 | 3.40 | 1.04 | | 2020 | 27 | MLB | NL | COL | | | | | | | | | | 11.1 | 15 | 10 | 10 | 3 | 3 | 0 | 13 | 1 | 1 | 7.94 | 1.59 | | 2020 | 27 | MLB | NL | COL | | | | | | | | | | 12.2 | 18 | 11 | 10 | 3 | 6 | 0 | 14 | 2 | 0 | 7.11 | 1.89 | | 2021 | 28 | MLB | NL | COL | | | | | | | | | | 31.1 | 35 | 15 | 14 | 4 | 8 | 0 | 32 | 0 | 2 | 4.02 | 1.37 | | 2021 | 28 | MLB | NL | COL | | | | | | | | | | 30.1 | 36 | 17 | 16 | 4 | 13 | 0 | 28 | 2 | 5 | 4.75 | 1.62 | | 2022 | 29 | MLB | NL | COL | | | | | | | | | | 29.2 | 24 | 17 | 15 | 6 | 11 | 0 | 24 | 0 | 1 | 4.55 | 1.18 | | 2022 | 29 | MLB | NL | COL | | | | | | | | | | 27.1 | 20 | 10 | 7 | 1 | 12 | 1 | 30 | 1 | 1 | 2.30 | 1.17 | | 2023 | 30 | MLB | AL | LAA | | | | | | | | | | 27.1 | 30 | 19 | 16 | 4 | 19 | 5 | 31 | 1 | 0 | 5.27 | 1.79 | | 2023 | 30 | MLB | AL | LAA | | | | | | | | | | 35.0 | 32 | 15 | 11 | 3 | 12 | 0 | 47 | 4 | 3 | 2.83 | 1.26 | | 2024 | 31 | MLB | | TOT | | | | | | | | | | 26.1 | 20 | 8 | 6 | 3 | 7 | 3 | 25 | 0 | 1 | 2.05 | 1.03 | | 2024 | 31 | MLB | | TOT | | | | | | | | | | 28.2 | 18 | 10 | 9 | 2 | 5 | 1 | 25 | 1 | 1 | 2.83 | 0.80 | | 2025 | 32 | MLB | AL | KC | | | | | | | | | | 34.2 | 29 | 12 | 11 | 3 | 16 | 5 | 29 | 1 | 1 | 2.86 | 1.30 | | 2025 | 32 | MLB | AL | KC | | | | | | | | | | 31.1 | 19 | 10 | 7 | 2 | 6 | 1 | 25 | 3 | 0 | 2.01 | 0.80 | | Totals | | | | | W | L | Win% | SV | G | GS | GF | CG | ShO | IP | H | R | ER | HR | BB | IBB | SO | HB | GIDP | ERA | WHIP |
| Career | vs LH | | | | | | | | | | 226.0 | 222 | 117 | 105 | 28 | 98 | 19 | 208 | 5 | 10 | 4.18 | 1.42 | | Career | vs RH | | | | | | | | | | 259.1 | 233 | 124 | 109 | 31 | 85 | 4 | 286 | 18 | 14 | 3.78 | 1.23 |
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| Year | Age | Lvl | Lg | Org | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| 2018 | 25 | AAA | PCL | | 28 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 | | Totals | | | | | G | AB | R | H | 2B | 3B | HR | RBI | BB | IBB | SO | SB | CS | SH | SF | HB | GIDP | BA | OBA | SLG | OPS |
| Minors | Minors | 28 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .000 | .000 | .000 | .000 |
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